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Clarinex is an antihistamine that provides relief of seasonal allergy symptoms and allergic nasal conditions (rhinitis) such as runny nose, sneezing, Home About Our Team Programs. Clarinex-D 12 Hour is used to treat sneezing, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold. Also, a doc can write a 30 day px for Claritin-D and it will override the 2 week limit that some states have for otc purchase of claritin-d or like drugs Clarinex (desloratadine) is a non-drowsy, once-daily medication used for allergy relief and chronic hives. Approval date: December 3, 2010. Probably because I am taking Claritin-D as we speak. Unlike most other allergy medications, it is not available over-the-counter. 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